7. 结果(Results)：说明主要客观结果

　　8. 结论(Conclusion)：说明主要结论，包括直接临床应用意义

　　Objectives: To determine whether a computerized decision support system for initiation and control of oral anticoagulant improves quality of anticoagulant control achieved by trainee doctors

　　Design: Randomized control trial

　　Setting: District general hospital in North London

　　Subjects: 148 inpatients requiring start of Warfarin (华法灵/苄丙酮香豆素) treatment

　　Interventions: Management by trainee doctors (to achieve therapeutic range of international normalized ration of 2 to 3) with indirect assistance from computerized decision support system (intervention group) or without such assistance (control group)

　　Main outcome measures: Median time to therapeutic range, stable dose, and firast pseudoevent (excessive international normalized ratio after therapeutic range had been reached) and person time spent in the therapeutic range

　　Results: 72 patients were randomized to the intervention group and 76 to control group. Median time to reach international normalized ratio of >2 was not significantly different in the two groups (3 days). Median time to achieve a stable dose was significantly lower in intervention group than in controls (7 days v 9 days, p<0.01) without excessive overtreatment or undertreatment with anticoagulant. Patients in intervention group spent greater proportion of time in therapeutic range, both as inpatients (59% v 52%) and outpatients (64% v 51%).

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